Xylitol, also called wood sugar or birch sugar, is a five-carbon sugar alcohol that is used as a sugar substitute. It can be extracted from birch, raspberries, plums, and corn and is primarily produced in China.
Xylitol, gram for gram, is roughly as sweet as sucrose, but contains 40% less food energy. Its formula is C5H12O5, with relative mass 152.15 amu. The molecule's systematic name is (2,3,4,5)tetrahydroxy-pentanol.
Dietary use worldwide
It is very popular in
Finland, which is considered its "home country". Many Finnish
confectioneries employ xylitol, or have a xylitol version available. Virtually all
chewing gum sold in Finland is sweetened with xylitol. The Spanish company
Chupa Chups makes a xylitol-based breath mint,
Smint, that it markets worldwide. In Japan and South Korea, xylitol is found in wide assortment of chewing gums. In
2004, popular North American
Trident gum was reformulated to include xylitol.
Medical applications
Dental care
Xylitol is a "
Toothfriendly" sugar substitute. In addition to discouraging tooth decay by replacing dietary sugars, xylitol may actively aid in repairing minor cavities caused by
dental caries. Recent research confirms a
plaque-reducing effect and suggests that the compound, having some chemical properties similar to
sucrose, attracts and then "starves" harmful micro-organisms, allowing the mouth to remineralize damaged teeth with less interruption. (However, this same effect also interferes with the
yeast micro-organism and others, so xylitol is inappropriate in making
bread, for instance.)
Diabetes
Possessing approximately 40% less food energy, xylitol is a low-
calorie alternative to table sugar, and is absorbed more slowly than sugar; thus it doesn't contribute to a rapid rise in
blood sugar level and the resultant
hyperglycemia caused by insufficient
insulin response.
Osteoporosis
Xylitol also appears to have potential as a treatment for
osteoporosis. A group of Finnish researchers have found that dietary xylitol prevents weakening of
bones in laboratory rats, and actually improves bone density.
[Mattila PT, Svanberg MJ, Jämsä T, Knuuttila ML (2002). Improved bone biomechanical properties in xylitol-fed aged rats. Metabolism 51(1):92-6. (online abstract)][Mattila, PT (1999). Dietary xylitol in the prevention of experimental osteoporosis: Beneficial effects on bone resorption, structure and biomechanics. Dissertation, Institute of Dentistry, University of Oulu. (online)]
Ear and upper respiratory infections
Studies
[Uhari M, et al. (1998). A novel use of xylitol sugar in preventing acute otitis media. Pediatrics, 102(4): 879–974.] [Drgreene.com] have shown that xylitol chewing gum can help prevent ear infections (acute
otitis media); the act of chewing and swallowing assists with the disposal of
earwax and clearing the
middle ear, whilst the presence of xylitol prevents the growth of bacteria in the
eustachian tubes which connect the nose and ear. This action that xylitol has on bacteria in the back of the nose is best explained on the site dealing with the nasal application of xylitol.
[Nasal-xylitol.com] When bacteria enter the body they hold on to our tissues by hanging on to a variety of sugar complexes. The open nature of xylitol and its ability to form many different sugar-like structures appears to interfere with the ability of many bacteria to adhere.
[Besttreaments.co.uk]
Candida yeast
A recent report suggests that consumption of xylitol may help control oral infections of
Candida yeast; in contrast,
galactose,
glucose and
sucrose may increase proliferation.
[ Abu-Elteen, Khaled H. The influence of dietary carbohydrates on in vitro adherence of four Candida species to human buccal epithelial cells. Microbial Ecology in Health and Disease (2005), 17(3), 156-162]
Health concerns
Xylitol, like most sugar alcohols, can have a mild
laxative effect at high doses. It has no known
toxicity, though; people have consumed as much as 400
grams daily for long periods with no apparent ill effects. For
canines, however, xylitol can cause serious – possibly life-threatening – problems. Dogs ingesting large amounts of products sweetened with xylitol may have a sudden drop in blood sugar, resulting in loss of coordination, depression and seizures within 30 minutes of consumption. There have been many cases in which the chemical is fatal to the dog, even the small amount of xylitol found in two or three pieces of Trident gum.
[ASPCA article]
References
See also
Sweeteners | Sugar alcohols
Xylitol | Xylitol | 자일리톨 | Xilitolo | Xylitol | キシリトール | Xylitol | Ksylitoli | Xylitol | 木糖醇