Wormwood may refer to:

• Various plants of the genus Artemisia, but commonly Artemisia absinthium.
• A suggested translation of Chernobyl (Artemisia vulgaris or "mugwort" is probably more accurate, but this is also called "wild wormwood")
• Wormwood, a star that falls onto the Earth poisoning the freshwater sources at the third trumpet in the end times (Book of Revelation 8:10-11)
• Wormwood Scrubs in west London
• Wormwood Scrubs prison
• A film entitled WORMWOOD Written & Directed by //www.zombiejunkyard.com/cast_crew/james_maynard.html James Maynard
• Wormwood, a character in The Screwtape Letters, a novel by C. S. Lewis.
• Curious Stories from the Bible, an album by The Residents.
• Wormwood (song), a song by Tristania.
• Miss Wormwood, a character in the comic strip Calvin and Hobbes
• Wormwood (band): a Doom Metal/Sludge Metal band from Lawrence, Kansas, USA