Tissue may refer to:

• Aerial tissue, an acrobatic art form and one of the circus arts
• Biological tissue, a group of biological cells that perform a similar function
• Tissue paper, a type of thin, translucent paper used for wrapping and cushioning items

• Facial tissue, a type of thin, soft, disposable paper used for nose-blowing (sometimes also referred to by the brand name Kleenex)