In chemistry, the sulfonamide functional group is -S(=O)₂-NH₂, a sulfone group connected to an amine group.

A sulfonamide (compound) is a compound that contains this group. The general formula is RSO₂NH₂, where R is some organic group. For example, "methanesulfonamide" is CH₃SO₂NH₂. Any sulfonamide can be considered as derived from a sulfonic acid by replacing a hydroxyl group with an amine group.

In medicine, the term "sulfonamide" is sometimes used as a synonym for sulfa drug, a derivative or variation of sulfanilamide.

See also

• Sulfa drug.

Functional groups | Sulfonamides

Sulfonamid | Sulfamidé | Sulfonamida | Sulfamidici | Sulfonamide | スルホンアミド | Sulfonamid | Sulfonamida | ซัลฟานิลาไมด์