The word originates from Latin substantia, literally meaning "standing under". The word was used to translate Greek philosophical term ousia.

Substance may refer to:

• Substance theory, in philosophy, that element of an object without which it would not exist, or what exists only by itself (causa sui)
• Chemical substance, in chemistry, a substance is an element or compound with uniform composition. If a substance is not a mixture it is called a pure substance
• Substance (medicine), in medicine, substance is any drug, chemical, or biologic entity, as well as any material capable of being self-administered or abused because of its physiologic or psychologic effects
• Substance (Joy Division album), a 1988 Joy Division compilation album of songs recorded in 1977–1980
• Substance 1987, a 1987 New Order album
• Substance design, a London-based design company
• Substance look-and-feel - an open-source look and feel for Java Swing applications

Látka (rozcestník) | Substanz | Substanco | 実体 | Substancja | Substance | Látka