A side chain in organic chemistry and biochemistry which is a part of a molecule that is attached to a core structure. An R group is a generic label for a side chain which can be anything; however, it is typically stable and covalently linked to the adjoining atom. Historically the abbreviations R and R-group, which often refer to side chains, come from the word "radical". (see also: functional group. Examples contained therein).

Examples

• In biochemistry, the peptide or protein side chains are the variable parts of amino acids extending from the peptide backbone.

Biochemistry | Organic chemistry

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