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The term "sequence analysis" in biology implies subjecting a DNA or peptide sequence to sequence alignment, sequence databases, repeated sequence searches, or other bioinformatics methods on a computer.

Sequence analysis in molecular biology and bioinformatics is an automated, computer-based examination of characteristical fragments, e.g. of a DNA-strand. It basically includes five biologically relevant topics:

  1. the comparison of sequences in order to find similar sequences (sequence alignment)
  2. identification of gene-structures, reading frames, distributions of introns and exons and regulatory elements
  3. prediction of protein structures
  4. genome mapping
  5. comparison of homologous sequences to construct a molecular phylogeny

In chemistry, sequence analysis comprises techniques used to determine the sequence of a polymer formed of several monomers. In molecular biology and genetics, the same process is called simply "sequencing."

Bioinformatics

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This article is licensed under the GNU Free Documentation License. It uses material from the "Sequence analysis".

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