Rose spots are red macular lesions 2-4 millimeters in diameter occurring in patients suffering from Salmonella infection, also known as typhoid fever and paratyphoid. These fevers occur following infection by the Salmonella typhi and Salmonella paratyphi bacteria respectively. Rose spots may also occur following invasive non-typhoid salmonellosis. Rose spots occur in approximately 50% of cases of typhoid fever, and are a classic symptom of the disease. They appear as a rash between the seventh and twelfth day from the onset of symptoms. They occur in groups of five to ten lesions on the lower chest and upper abdomen, and they are more numerous following paratyphoid infection. Rose spots typically last three to four days.
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