A pseudocyst is a pathological collection of fluid. A pseudocyst may appear to be a true cyst to the naked eye or on a CAT scan. However, it is technically not a cyst. The wall of a true cyst consists of a clearly defined epithelial cell layer. The wall of a pseudocyst consists of granulation and/or fibrous tissue (which is present secondary to inflammation).

A pancreatic pseudocyst results from the passage of inflammatory fluid into the omental bursa. This is typically a complication of acute pancreatitis, but may also occur following abdominal trauma.

Anatomical pathology