Phosphoenolpyruvate carboxylase (or PEPCase) is an enzyme in the family of carboxy-lyases. They convert oxaloacetate into phosphoenolpyruvate, and carbon dioxide.

It is classified under EC number 4.1.1. There are three main types, distinguished by the source of the energy to drive the reaction:

• 4.1.1.32 - GTP
• 4.1.1.38 - diphosphate
• 4.1.1.49 - ATP

See also

• gluconeogenesis

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