Paralysis is the complete loss of muscle function for one or more muscle groups. Major causes are stroke, trauma, poliomyelitis, amyotrophic lateral sclerosis (ALS), botulism, spina bifida, multiple sclerosis, and Guillain-Barré syndrome. Paralysis is most often caused by damage to the nervous system or brain, especially the spinal cord. Paralysis often includes loss of feeling in the affected area.

Paralysis may be localized, or generalized, or it may follow a certain pattern. For example, localized paralysis occurs in Bell's palsy where one side of the face may be paralysed due to inflammation of the facial nerve on that side. Patients with stroke may be weak throughout their body (global paralysis) or have hemiplegia (weakness on one side of the body) or other patterns of paralysis depending on the area of damage in the brain. Other patterns of paralysis arise due to different lesions and their sequelae. For example, lower spinal cord damage from a severe back injury may result in paraplegia, while an injury higher up on the spinal cord, such as a neck injury, can cause quadriplegia.

Most paralyses caused by nervous system damage are constant in nature; however, there are forms of periodic paralysis, including sleep paralysis, which are caused by other factors.

Poisons that interfere with nerve function, such as curare, can also cause paralysis.

Famous people with paralysis include the late actor Christopher Reeve; the architect Michael Graves; Sam Sullivan, mayor of Vancouver, British Columbia, Canada; and Jesse Billauer from the movie Step Into Liquid; and hundreds of thousands of others around the world.

Implant Potential Breakthrough

---

In what is being heralded as a potential breakthrough for patients with spinal cord injuries, a quadriplegic was able to open e-mail, change television stations and turn on lights with just his mind -- and a sophisticated brain sensor that translated his thoughts into actions.*^* Article shows RealVideo:

• Matthew Nagle on being a BrainGate study participant
• RealVideo: A patient opens simulated e-mail
• RealVideo: A patient controls a prosthetic hand
• RealVideo: A patient operates a robotic limb

How it works:^*

Paralysis in the animal world

---

Many species of animals use paralyzing toxins in order to capture prey, evade predation, or both. One famous example is the tetrodotoxin of fish species such as Takifugu rubripes, the famously lethal pufferfish of Japanese fugu. This toxin works by binding to sodium channels in nerve cells, preventing the cells' proper function. A non-lethal dose of this toxin results in temporary paralysis. This toxin is also present in many other species ranging from toads to nemerteans. Another interesting use of paralysis in the natural world is the behavior of some species of wasp. In order to complete the reproductive cycle, the female wasp first paralyzes a prey item such as a grasshopper and then places it into her nest. Eggs are then laid on the paralyzed insect, which is devoured by the larvae after they hatch. Many snakes also exhibit powerful neurotoxins that can cause non-permanent paralysis or death.

See also

---

• Paraplegia
• Quadriplegia
• Muscle relaxant
• Ptosis
• Sleep paralysis
• Hemiparesis
• Beriberi
• Jesse Billauer
• Neuroprosthetics
• Brain-computer interface
• Tonic immobility

Neurological disorders | Symptoms

Lähmung | Paralysie | שיתוק | 麻痺 | Verlamming | Halvaus

Link

---

• ^*Implant lets disabled man use his brain to do tasks