Nuke or nuking can refer to multiple things:

• A colloquialism for nuclear weapon, or the use of one
• Terms referring to heating something in a microwave oven
• Nuke (computer), a denial-of-service attack
• WinNuke, an exploit in some early versions of Microsoft Windows
• Terms used in warez communities, see nuker
• For the meaning in the context of role-playing games, see nuke (gaming)
• Nucleoside/Nucleotide Reverse Transcriptase Inhibitors, better known as nucleoside analogues or Nukes were the first group of available antiretroviral drugs to treat HIV in 1987
• Fictional drug in RoboCop 2
• Nuke (comics), an American Flag faced comic book Marvel Comics character
• Nuke (Squadron Supreme), a superhero from Earth-712 in the fictional Marvel Universe
• Nuke (software), a digital compositing software by Digital Domain
• A family of simple content management systems that provide basic functionality in the form of user management and news item editing, and add in more functionality, such as calendars and forums, through the use of modules
  • OpenPHPNuke
  • PHP-Nuke
  • PostNuke
  • CPG-Nuke
  • DotNetNuke
  • Mambo (CMS)
  • Joomla
• First phrase of the online, textbased strategy game NukeZone

Nuke