In human embryology, formation of neural plate is the first step of neurulation. It is created by a flat thickening opposite to the primitive streak.

As it develops, it becomes surrounded by neural folds, which eventually create the cylindrical neural tube. This process is termed primary neurulation.

The inhibitory signals chordin, noggin and follistatin are needed to form the neural plate.

External links

• Diagram at temple.edu
• Overview at embryology.ch
• Overview and diagram at brown.edu, with focus upon signaling
• Neural plate formation in mouse, at swarthmore.edu

Embryology