Mononeuritis multiplex is the clinical picture that arises from problems with multiple individual nerves serially or almost simultaneously.

Synonyms

---

Mononeuropathy multiplex

Clinical findings

---

Mononeuritis multiplex typically presents with the acute or subacute evolution of loss of sensory and motor function of individual peripheral nerves. The pattern of involvement is asymmetric.

Diagnosis

---

Electrodiagnostic studies will show multifocal sensory motor axonal neuropathy.

Causes and associations

---

Mononeuritis multiplex is associated with diabetes mellitus, polyarteritis nodosa and other vasculitides (Wegener granulomatosis, Churg-strauss syndrome), rheumatoid arthritis, sarcoidosis, and amyloidosis. Infections such as leprosy, Lyme disease and HIV have also been known to cause Mononeuritis multiplex.

Diseases