Mexiletine

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Mexiletine belongs to the Class IB anti-arrhythmic group of medicines. It is used to treat arrythmias within the heart - or serriously irregular heartbeats. It slows nerve impulses in the heart and makes the heart tissue less sensitive. Dizziness, heartburn, nausea, nervousness, trembling, unsteadiness are common side effects. It is available in injection and capsule form.

Class IB antiarrhythmics decrease action potential duration by shortening the repolarization phase. This is achieved by blocking sodium channels.

External Links

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• MedlinePlus Drug Information: Mexiletine

References

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• Peck, Hill & Williams editors Pharmacology for Anaesthesia and Intensive Care (2nd Edition). Cambridge: 2004. ISBN 0-521-687942