Lingual lipase is an enzyme found in the saliva that breaks down lipids. Specifically, it breaks down triglycerides into fatty acids and monoglycerides. The enzyme works over a wide range of pH, therefore it starts breaking down lipids in the mouth and can still function in the acidic (pH = 1) environment of the stomach. In contrast to pancreatic lipase, it can cleave fatty acids from all three positions of a fat molecule. Pancreatic lipase can only cleave at the 1st and 3rd Carbon of glycerol.
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