Helix can mean several things:

• Helix, the shape
• Helix (genus), the genus of terrestrial snails
• Helix project, the open-source media project
• Helix database, the Macintosh-based database management system
• Helix (band), a Canadian heavy-metal band.
• Helix (cipher), a stream cipher
• Helix (cars), a Hungarian carmarket
• Helix (ear), the outer part of the outer ear^*
• Webcomic Freefall has a robot character named Helix.
• The Helix was an underground newspaper in Seattle.
• Helix is also the NATO reporting name of the Kamov Ka-27 helicopter.
• Helix Ltd, a British-based stationery company
• The Helix is a theatre in Dublin in the Republic of Ireland.