The heart sounds are the noises (sound) generated by the beating heart and the resultant flow of blood through it. In cardiac auscultation, an examiner uses a stethoscope to listen for these sounds, which include heart tones, or sounds, produced by sudden blood deceleration after the heart valves close, heart murmurs, and adventitious sounds, or clicks.
Heart sounds are usually divided into the normal heart sounds and the pathological sounds which indicate disease. The two distinct normal heart tones are often described as a lub and a dub (or dup), and occur in sequence with each heart beat. Murmurs are generated by turbulent flow of blood within the heart. Stenosis, or impaired opening of a heart valve, causes turbulence as blood flows through it. Valve insufficiency, or regurgitation, allows backflow of blood when the valve is supposed to be closed. In these situations, murmurs will be heard in the corresponding part of each cardiac cycle.
During inspiration, negative intrathoracic pressure causes increased blood return into the right side of the heart. The increased blood volume in the right ventricle causes the pulmonic valve to stay open longer during ventricular systole. This causes an increased delay in the P2 component of S2. During expiration, the positive intrathoracic pressure causes decreased blood return to the right side of the heart. The reduced volume in the right ventricle allows the pulmonic valve to close earlier at the end of ventricular systole, causing P2 to occur earlier, and "closer" to A2. It is physiological to hear the splitting of the second heart tone by younger people and during inspiration. During expiration normally the interval between the two components shortens and the tone becomes merged.
With the advent of newer, non-invasive imaging techniques, the origin of other, so-called adventitial sounds or "clicks" has been appreciated. These are short, high-pitched sounds.
Many cardiac conditions can cause heart murmurs. However, the murmurs produced often change with the severity of the cardiac disease. Often, the astute physician can diagnose a cardiac condition solely on the murmur and related physical examination.
There are a number of interventions that can be performed that alter the intensity and characteristics of abnormal heart sounds. These interventions can be performed to differentiate the different heart sounds and obtain a diagnosis of the cardiac anomaly that causes the heart sound. (See Heart murmur#Interventions that change murmur sounds.)
Inhalation pressure also causes an increase in the venous blood return to the right side of the heart. Therefore, right-sided murmurs generally increase in intensity with inspiration. The increased volume of blood entering the right sided chambers of the heart restricts the amount of blood entering the left sided chambers of the heart. This causes left-sided murmurs to generally decrease in intensity during inspiration.
With expiration, the opposite hemodynamic changes occur. This means that left sided murmurs Similar to inhalation increased blood flow to the right side of the heart can be facilitated by having the patient lie supine and raising their legs up to a 45 degree angle.
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