Glucocerebrosidase (also called glucosylceramidase or D-glucosyl-N-acylsphingosine glucohydrolase) is an enzyme () that is needed to break down the chemical glucocerebroside by hydrolysis. It is localized in the lysosome and has a molecular weight of 59700 Da. It is the enzyme that is defective in cells of patients with Gaucher disease.

EC 3.2.1 | グルコセレブロシダーゼ