Fructosamine, also known as Glycated Serum Protein (GSP) or Glycated Albumin, is used primarily to identify the plasma glucose concentration over time and so assess diabetic control .

Indications

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More commonly diabetics have their average control assessed with the Glycosylated hemoglobin measurement that indicates glucose levels over the preceding 6 weeks; as reflected by the perminant glycosylation of a small fraction of the hemoglobin molecules in their blood. However this is not appropriate where there has been a recent change in diet or treatment within 6 weeks, nor if there are abnormalities of red blood cell aging process or mix of haemaglobin subtypes (predominantly HbA in normal adults). Hence people with recent blood loss or hemolytic anemia, or hemoglobinopathy such as sickle-cell disease are not suitable for Glycosylated hemaglobin test. The Fructosamine test is used instead in these circumstances and it similarly reflects an average of blood glucose levels, but over a shorter period of 2 to 3 weeks.

Interpretation of results

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There is no standard reference range available for this test. The reference values depends upon the factors of patient age, gender, sample population and test method. Hence each laboratory reports will include their specific reference range for the test.

See also

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• Diabetes mellitus

Diabetes | Hematology | Proteins