An endpoint or end point is a mark of termination or completion.

• In geometry, an endpoint is a point at which a line segment or ray terminates.
• In chemistry, an endpoint is the conclusion of a chemical reaction. In particular, in a titration, it is the point at which no further titrant should be added — usually indicated by a colour change in an indicator or some other measurable change.
• In computer science, in discussions of communications protocols, an endpoint is the name for the entity on one end of a transport layer connection.
• In music, Endpoint is the name of a hardcore band.
• In a research trial, a clinical endpoint refers to a disease, symptom, or sign that constitutes one of the target outcomes of the trial.