Confluence may refer to:

• Confluence (geography), the point where two or more rivers meet and merge
• Confluence (Degree Confluence Project), the intersection of whole number latitude and longitude
• Confluence language, a hardware description language
• Confluence (term rewriting), a property of term rewriting systems
• Confluency, the percentage of capacity of a cell culture medium used by cells
• Atlassian Confluence, a knowledge management tool
• Confluence Holdings Corp., the largest manufacturer for canoes, kayaks and accessories worldwide
• Confluence Corporation, a provider of information technology support services to nonprofits
• Confluence a wiki software by Atlassian Software Systems