Co-codamol (BAN) is a non-proprietary name used to denote a combination of codeine phosphate and paracetamol (acetaminophen). Co-codamol tablets are used for the relief of mild/moderate (or in the case of 30/500mg - severe) pain.

Three strengths are available: -

• 8mg of codeine phosphate per tablet
• 15mg of codeine phosphate per tablet
• 30mg of codeine phosphate per tablet (available in capsules as Tylex and Kapake, available in tablets as Solpadol)

All formulations contain 500mg of paracetamol per tablet. In the United Kingdom, the 500+15 mg and 500+30 mg tablets are available only with a prescription. This is also the case in Australia, however 500+15 mg tablets in packs of 12 or less are Schedule 3 (Pharmacist Only Medicine).

Co-codamol is marketed in the United States as Tylenol with Codeine #1/#2/#3/#4.

Side effects

• Skin rashes
• Hypersensitivity reactions
• Constipation
• Nausea
• Confusion
• Drowsiness
• Vomiting
• Changes in blood
  • Easy bruising
  • Bleeding gums

Analgesics