CMS is a three-letter acronym that can refer to:

Organizations

• Calexico Mission School, Adventist School in Calexico CA, USA
• Canadian Mathematical Society, a professional society for mathematicians
• Centers for Medicare & Medicaid Services, a federal agency in the United States
• Charlotte-Mecklenburg Schools, school district in North Carolina, USA
• Church Missionary Society
  • C. M. S. College, in Kottayam, Kerala, India
  • CMS Federal Training College, Australia (St Andrew’s Hall) adjacent to Ridley College (University of Melbourne)
• CMS Energy
• Cyprus Mathematical Society, a professional society for mathematicians
• Careers Management Services, a organization that aims to help people in their career.

Computing

• Content management system, a script or program for maintaining web sites
• Code management system, a script or program for archiving and maintaining source code
• Conversational Monitor System, an IBM operating system
• CMS-2 programming language, used by the United States Navy
• Cryptographic Message Syntax, a cryptographic standard
• Component Management System, used in some PCB design packages

Science

• Color management system, used to obtain a good match across color devices
• Compact Muon Solenoid detector, a particle physics experiment
• Communication management system, in the telecommunication industry

Miscellaneous

• Chronic mountain sickness, also known as Monge's disease, a disease caused by living a long time at high altitude
• Changeable Message Sign, a variable road sign
• The Chicago Manual of Style, a guide to American English publication style
• Constant Maturity Swap, a type of financial swap
• Critical Management Studies, a left wing approach to management, business and organisation
• Cms, a minor angel in Enochian
• Cabin Management System, digital control of all the In Flight Entertainment within an Aircraft
• Clinical Management System, software managing electronic medical records and practice management information

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