Chrome may refer to:

• Chrome plating, where the element chromium is fixed to a surface
• Chrome (band), a music group from San Francisco that was most active from the late 1970s to the 1980s
• Chrome (song), a song from Debbie Harry's debut solo album Koo Koo
• Burning Chrome, a series of short stories by William Gibson
• User interface chrome, the borders and widgets that frame the content part of a "window"
• Chrome (game), a sci-fi FPS by Techland
• Chrome (rapper)
• Chrome (XM), channel 83 on XM Satellite Radio
• Chrome programming language, an Object Pascal implementation of the .NET Framework