• In medicine, a bolus (from Latin bolus, ball) is a large dose of a medication that is given (usually intravenously by direct infusion injection or gravity drip) at the beginning of treatment to raise blood-level concentrations to a therapeutic level.
  • Diabetics and health care professionals use bolus to describe a dosage of fast-acting insulin intended to "cover" a meal (as opposed to basal, which is either a dose of slow-acting insulin or a continuously pumped small quantity of fast-acting insulin, intended to "cover" the glucose output of the liver).
• In biology, a bolus is any kind of ball-shaped organic structure of an organism or of its discharged substances.
  • The term is also used for any fairly large quantity of matter, usually food, making its way through the digestive tract. In some technical domains it is used to describe the solid results of a bowel movement.
• The Jacquard loom uses an instrument called the Bolus hook.

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