Angiotensin I converting enzyme 2 (ACE2) (EC 3.4.15.1) is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin^* . ACE 2 has direct effects on cardiac function, and is expressed predominantly in vascular endothelial cells of the heart and the kidneys .

See also

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• Renin-angiotensin system
• ACE inhibitors

References

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Donoghue M, Hsieh F, Baronas E, Godbout K, Gosselin M, Stagliano N, Donovan M, Woolf B, Robison K, Jeyaseelan R, Breitbart RE, Acton S. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 2000;87:E1-9. Free text

Boehm M, Nabel EG. Angiotensin-converting enzyme 2--a new cardiac regulator. N Engl J Med 2002;347:1795-7.

EC 3.4.15