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Adventitia is the outermost connective tissue covering of any organ, vessel, or other structure. For example, the connective tissue that surrounds an artery is called the adventitia because it is considered extraneous to the artery.
The Tunica Adventitia is the outermost layer of a blood vessel, surrounding the tunica media. It is mainly composed of collagen. A common pathological disorder concerning the Tunica Adventitia is scurvy, also known as vitamin C deficiency. Scurvy occurs because vitamin C is essential for the synthesis of collagen, and without it, the faulty college cannot maintain the vein walls, and they rupture, leading to a wide multitude of problems.
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"Adventitia"