Wyandotte is the name of some places in the United States of America:

• Wyandotte, Michigan
• Wyandotte, Oklahoma
• Wyandotte County, Kansas
• Wyandotte Township, Minnesota

There is also a cave named Wyandotte Cave in Indiana.

Wyandotte is an alternative spelling of Wyandot or Wendat, the name of a First Nations group also called Hurons.

Wyandotte is a novel by James Fenimore Cooper.

Wyandotte is a breed of chicken.