A tyrant originally referred to a ruler in Ancient Greece who seized power by force, usually with popular support. See List of Ancient Greek tyrants. In modern usage, the word tyrant refers to any despotic ruler.

Tyrant may also refer to:

• Tyrant (computer game), an open source Roguelike
• Tyrant (Resident Evil), a monster from Resident Evil
• Tyrant Virus, a fictional virus also from Resident Evil
• Tyrant flycatchers, a family of birds
• Tyrant is a character in the City of Heroes online computer role-playing game (MMORPG)
• Tyrant is a song on Sad Wings of Destiny, an album by Judas Priest.
• Blast Tyrant is an album by Clutch.