Tsholotsho (formerly known as Tjolotjo) is a village in Matabeleland North, Zimbabwe and is located about 65km north-west of Nyamandhlovu in the Tjolotjo communal land. An industrial school was founded here in 1921 but was relocated to Esigodini in 1941 and the old buildings taken over by the Matopos Research Station where cattle breeding is researched.

Districts around Tsholotsho include Lupane, Hwange, and Plumtree.

It was the location of a mass killing in 1983, as part of Robert Mugabe's "Gukurahundi" genocide of the Ndebele people.

Villages in Zimbabwe | Tsholotsho