Tree of Knowledge may refer to:

• The Tree of Knowledge of Good and Evil mentioned in the Book of Genesis
• The Bodhi tree under which the Buddha received enlightenment according to Buddhism
• The metaphysical Tree of Jiva and Atman in Vedic mythology
• The Axis mundi, or world axis, which takes the form of a tree in Christian mythology
• Drvo Znanja (Tree of Knowledge), Croatian encyclopedic magazine.
• A novel by Pío Baroja, "El árbol de la ciencia", translated as Tree of Knowledge (1974), Howard Fertig.
• Ramon Llull wrote the Tree of Science (1295).
• The traditional birthplace of the Australian Labor Party is a Ghost Gum in Barcaldine, Queensland.

La arbo de la sciado