The Lancet is one of the oldest and most respected peer-reviewed medical journals in the world, published weekly by Elsevier, part of Reed Elsevier. It was founded in 1823 by Thomas Wakley, who named it after the surgical instrument called a lancet, as well as an arched window ("to let in light").
The present editor-in-chief is Richard Horton. The Lancet is, and has been, outspoken on several important medical issues - recent examples include criticism of the WHO, rejecting the efficacy of homoeopathy as a therapeutic option and its disapproval of Reed Elsevier's links with the arms industry.
However, it was subject to severe criticism after it published a paper in 1998, in which the authors raised the possibility of a link between MMR vaccine and autism, a matter of continuing controversy. In February 2004 The Lancet published a partial retraction of the paper. Dr Horton went on the record to say the paper was "fatally flawed" because one of the authors had a serious conflict of interst that he had not declared to The Lancet. When it published an estimate of Iraq civilian death toll - at least one hundred thousand - just two days before the November 2004 US Presidential Elections, it was accused of being political.
In January 2006, it was revealed that data had been fabricated in an article by the cancer researcher Jon Sudbø and 13 co-authors published in The Lancet in October 2005, The fabricated article was entitled "Non-steroidal anti-inflammatory drugs and the risk of oral cancer: a nested case-control study". [http://www.aftenposten.no/nyheter/iriks/article1199644.ece. Within a week after this scandal surfaced in the news, the high-impact New England Journal of Medicine published an expression of editorial concern regarding another research paper published on a similar topic in the journal.
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