TCR can mean:

• Toronto Civic Railways
• Total Control Racing, a slotless track mini-car racing that lets you control your car
• Tottenham Court Road, a street in London which Tottenham Court Road tube station is named after
• TCR (music), the musical project of Robin Moulder and TC of Satiate.
• A single by the band Prolapse
• T cell receptor
• A joint venture between Brambles Industries and German airport company Fraport AG
• Transmission Control Room
• Transcription-coupled repair a DNA repair mechanism
• The Colbert Report, a parody news show on Comedy Central
• Thyroid Cartilage Reduction or Chondrolaryngoplasty