Susquehanna may refer to the following places in the U.S. state of Pennsylvania:

• Susquehanna County, Pennsylvania
• Susquehanna Steam Electric Station, a nuclear power plant
• Susquehanna Depot, Pennsylvania, a borough in Susquehanna County
• Susquehanna River, a tributary of Chesapeake Bay
• Susquehanna Township, Cambria County, Pennsylvania
• Susquehanna Township, Dauphin County, Pennsylvania
• Susquehanna Township, Juniata County, Pennsylvania
• Susquehanna Township, Lycoming County, Pennsylvania
• Susquehanna Trails, Pennsylvania, a census-designated place in York County

Susquehanna may refer to the following Pennsylvania institutions:

• Susquehanna Bank
• Susquehanna International Group, a leading institutional sales, research and market making firm.
• Susquehanna University in Selinsgrove, Pennsylvania.

Susquehanna may refer to a ship of the US Navy:

• USS Susquehanna Disambiguation page for ships of this name.