There have been a number of notable people named Roy Brown:

• Roy Brown, the Canadian pilot who is credited with shooting down the Red Baron
• Roy Brown (1925–81), a blues musician who was a pioneer of rock and roll
• Roy Brown Ramírez (b. 1950), a Puerto Rican musician and folk singer
• Roy Brown - clown, puppeteer and artist most famous for his role as sidekick "Cooky the Cook" on WGN-TV Chicago's "Bozo's Circus" and "The Bozo Show"
• Roy 'Chubby' Brown, a British comedian
• Roy Brown Alberta politician
• Roy Brown A Montana state representative
• Roy W Brown - president of the IHEU
• Roy Brown CEO of Ohio's Brown Publishing Company.