Reuben Chase (23 June 1754 – 23 June 1824) was an officer in the Continental Navy.

Chase joined Ranger as a seaman in 1777 and served during John Paul Jones' daring raid into British waters. Chase was appointed a midshipman in Bonhomme Richard 18 March 1779, and took part in the historic victory over HMS Serapis 23 September 1779.

Chase (DD-323) was named in his honor.

Continental Navy officers