Poe may refer to:

People named Poe

• Edgar Allan Poe (1809-1849), a famous American writer
• Poe (born 1968), the stage name of rock singer-songwriter Ann Danielewski
• John Poe (fl. 1980s), the drummer from rock band Guadalcanal Diary
• Poe Darli Theintan (fl. 1990s), a Burmese vocalist
• Michael Poe (fl. 2000s), an American webcomics artist

Fictional characters

• Poe, a ghost-like creature in video games of The Legend of Zelda series
• Poe, a poet in computer games of the Baldur's Gate series
• Poe, the third mascot of the Baltimore Ravens National Football League team
• Mr. Poe, the banker from A Series of Unfortunate Events
• Poe, a playable character from the Playstation 2 RPG The Azoth of Destiny.

Acronyms