Peyronie's disease is a rare connective tissue disorder involving the growth of fibrous plaques in the soft tissue of the penis affecting as much as 1% of men.

This may be associated with Dupuytren's contracture.

Causes

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The exact cause is not known, although it is thought to be caused by injury to the internal cavity of the penis, which results in bleeding and later scar tissue formation at the tunica albuginea of the corpora cavernosa.

It is also thought that this is a hereditary disease.

Variation

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A certain degree of curving of the penis is considered normal.

Note: It is common and normal for a penis to have some small degree of bend at the base, causing the penis to point in a direction other than directly forward, while still having a straight shaft. This is not caused by Peyronie's disease or masturbation.

Symptoms

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It may cause pain, cord-like lesions, or abnormal curvature of the penis when erect. It may also make sexual intercourse painful, although some men report enjoyable intercourse in spite of the disease.

Diagnosis and treatment

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A urologist can diagnose the disease and suggest treatment, though treatment is limited since Peyronie's disease is not fully understood. Treatment usually takes the form of surgery and oral medications. Tablets of vitamin E 800 mg/day or potassium aminobenzoate (Potaba) 12 g/day may produce some improvement; you will need a doctor’s prescription. Don’t be tempted to take higher doses of vitamin E.

See also

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• Hypospadias

External links

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• http://www.peyroniesforum.net/index.php

Eponymous diseases | Sexual health | Andrology | Penis

Induratio penis plastica | Maladie de La Peyronie | Induratio penis plastica | מחלת פיירוני | Ziekte van Peyronie