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Paget's disease of the breast, also known as Paget's disease of the nipple, is a condition that outwardly may have the appearance of eczema - with skin changes involving the nipple of the breast. Usually only affecting one nipple, there may be redness, oozing and crusting, and a sore that does not heal.
Paget's disease is caused by breast cancer and is present in about 2% of all breast cancers. It typically results when malignant cells from an underlying carcinoma that originated in the ducts of the mammary glands spread to the epithelium.
Recommended tests are a mammogram and a biopsy to confirm the diagnosis.
Treatment usually involves some kind of mastectomy to surgically remove the tumour. Chemotherapy and/or radiotherapy may be necessary.
The condition is named after Sir James Paget, an English surgeon who first described it in 1874.
External links
"Paget's disease of the breast"