New York State Route 49 (NY Route 49 or NY 49) is a state highway in the U.S. state of New York. It runs from NY Route 3 east of Fulton to Interstate 790, NY Route 5, NY Route 8 and NY Route 12 in Utica. A portion of it between Rome and Utica is known as the Utica-Rome Expressway.
| Destinations | Notes |
|---|---|
| westbound exit and eastbound entrance | |
| westbound exit and eastbound entrance | |
| NY Route 69 east; NY Route 233 south - Stanwix; Westmoreland | NY 69 joins westbound and leaves eastbound |
| westbound exit is combined with NY 825 exit; NY 365 joins westbound and leaves eastbound | |
| Griffiss Park (NY Route 825 north) | |
| Oriskany | |
| NY Route 291 - Whitesboro; Stittville; Marcy Business District | |
| Cavanaugh Road - Whitesboro | |
| Edic Road | no westbound entrance |
| eastbound exit and westbound entrance | |
| eastbound exit and westbound entrance | |
| eastbound exit and westbound entrance |
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"New York State Route 49".
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