The Nanticoke Indian Tribe is a Native American tribe from Sussex County, Delaware comprising the Nanticoke River watershed which empties into the Chesapeake Bay. The area has been home to an indigenous population of Delaware, or Leni Lenape indians since pre European times. An annual pow-wow is held near Oak Orchard, Delaware. This pow-wow features some descendants of original Nanticoke Indian populations and representatives of other tribes and nations.

Evidence for the early population of the Delaware peninsula by Native Americans is easily found, arrow points, pottery shards, axe-heads and other items such as bone drills, etc, are turned up regularly in farmer's fields and some excavated sites along the riverbanks of the state have revealed evidence of long term settlement.

Native American tribes