Macsyma is a computer algebra system that was originally developed from 1967 to 1982 at MIT as part of Project MAC and later marketed commercially. It was the first comprehensive symbolic mathematics system and one of the earliest expert systems; many of its ideas were later adopted by Mathematica, Maple, and other systems.
Yannis Avgoustis (special functions), David Barton (algsys), Richard Bogen (special functions), Bill Dubuque (limits, Grobner, TriangSys, indefinite integration: Bronstein, power series, number theory, special functions, functional equations, pattern matching, sign queries), Richard Fateman (rational functions, pattern matching, arbitrary precision floating-point), Michael Genesereth (comparison, knowledge database), Jeff Golden (simplifier, language, system), R. W. Gosper (definite summation, special functions), John Kulp (plotting), Ed Lafferty (ODE solution, special functions), Stavros Macrakis (real/imaginary parts, system), Barry Trager (algebraic integration, factoring, Grobner), Paul Wang (polynomial factorization, limits, definite integration), David Y. Y. Yun, Gail Zacharias (Grobner), and Rich Zippel (power series, polynomial factorization, number theory, combinatorics).
Macsyma was written in Maclisp, and was, in some cases, a key motivator for improving that dialect of lisp in the areas of numerical computing, efficient compilation and language design. Maclisp itself ran primarily on PDP-6 and PDP-10 computers, but also on the Multics OS and on the Lisp Machine architectures. Macsyma was one of the largest, if not the largest Lisp program of the time.
Eventually Macsyma was also released for DEC VAX-11 computers and Sun Microsystems workstations using Berkeley's Franz Lisp.
In 1982, under pressure from contributor Richard Fateman, then at UC Berkeley, MIT licensed a copy of Macsyma to the United States Department of Energy, one of the major funders of Macsyma development. This version of Macsyma was called DOE Macsyma.
Macsyma, Inc., was founded in 1992 by Russell Noftsker (who had co-founded Symbolics). Macsyma Inc then purchased all rights to the Macsyma program away from the ailing Symbolics Inc. Under Richard Petti, Macsyma Inc accelerated its technical development and improved appearances, especially under Windows. Under heavy competition from Mathematica and Maple, Macsyma lost market share. In 1999, Macsyma was acquired by Tenedos LLC, a holding company. At present the holding company has not rereleased or resold Macsyma, but it continues to be distributed by Symbolics.