M50 or M-50 may be:

• BMW M50, a piston engine
• Myasishchev M-50 (NATO reporting name Bounder), a Soviet four-engine supersonic bomber prototype
• Ontos M50, anti-tank platform
• Open Cluster M50, a Messier object and open cluster in the Monoceros constellation
• Reising M50, a submachine gun
• Volvo M50 transmission, a gearbox

Highways and roads

• M50 motorway (Ireland), a road in the Republic of Ireland
• M50 motorway (United Kingdom), a road in England
• Michigan State Highway 50, a highway in Michigan, abbreviated M-50
• Mississippi State Highway 50, a highway in Mississippi, also abbreviated M-50

Lists of roads sharing the same title

M50