Lost may refer to:

• Lost (TV series), a television series about the survivors of a plane crash on a mysterious tropical island
• Lost (2001 TV series), a short-lived reality television program on NBC in the United States
• Lost, Scotland, a tiny hamlet in Scotland, west of the city of Aberdeen
• Lost (album), a 2003 album by hip hop artist Eightball
• Lost (film), a 1950s United Kingdom movie known as Tears for Simon in the United States
• Lost (2000 novel), a crime novel by Lucy Wadham, which won the 2000 Silver Dagger for best crime novel
• Lost (2001 novel), a revisionist novel by Gregory Maguire based on Charles Dickens's A Christmas Carol
• Lost (drink), a commercial energy drink created by Hansen's Beverage Company for Lost Enterprises
• Mustard gas, from LOmmel and STeinkopf who developed a process for mass-producing the gas for war.

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