Let's Go may refer to:

Television

• Let's Go (Philippine TV series), a teen Philippine sitcom on ABS-CBN
• Let's Go (New Zealand TV series), a New Zealand television music show
• Let's Go (CBC TV series), a 1960s Canadian television series on CBC Television
• Let's Go (CTV TV series), a 1970s-1980s Canadian children's television series on CTV television network
• Bakusou Kyoudai Let's & Go, an anime series which extensively promotes Tamiya's mini 4WD cars.

Music

• Let's Go (album), a punk rock album by Rancid
• "Lets Go" (single), a single by punk band, Liveonrelease
• "Let's Go" (song), a rap single by Trick Daddy featuring Lil Jon & Twista
• "Let's Go" (The Cars song), a song recorded by The Cars in 1979, covered by The Chipmunks in 1980

Other

• Let's Go (film), a 1918 short comedy film starring Harold Lloyd
• Let's Go Travel Guides