Last Island (also called Isle Derniere) was a barrier island and pleasure resort south-southwest of New Orleans on the south shore of Louisiana. It was utterly destroyed by the Last Island Hurricane of August 11, 1856. The highest points were under 5 ft of water. The resort hotel and surrounding gambling establishments were destroyed, over 200 people perished, and the island was left void of vegetation and split in half.

Last Island was south of Dulac, Louisiana, between Lake Pelto, Caillou Bay, and the Gulf of Mexico.

Last Island was a popular resort for people seeking to escape the humidity, illness, and insects of southern Louisiana. A resort hotel, several gambling establishments, and approximately 100 houses were constructed there, despite the fact it was a barrier island and the highest point was no more than 5 ft above sea level.

Last Island is now only a haven for pelicans and other seabirds.

History of Louisiana | Terrebonne Parish, Louisiana | Barrier islands