Janeway lesions are non-tender, small erythematous or haemorrhagic macules or nodules in the palms or soles, which are pathognomonic of infective endocarditis. The pathology is due to a type III hypersensitivity reaction.

They are named after Theodore Caldwell Janeway (1872-1917), a professor of medicine with interests in cardiology and infectious disease.

See also

• Osler's nodes (painful sign of endocarditis)
• Roth's spots (yet another sign of endocarditis)

Eponymous medical signs