James Harrison:

• James Harrison (engineer) (1816—1893) was an Australian engineer who developed an ice-making machine
• James Harrison (Australian governor) (1912—1971) was the first Australian appointed as Governor of South Australia, in 1968
• James Harrison (politician) was an Australian Labor Party member of the Australian House of Representatives from 1949 to 1969 representing the Division of Blaxland
• James M. Harrison, a Canadian scientist and public servant
• James Harwood Harrison, commonly known as Harwood Harrison, a former British Conservative Member of Parliament
• James Harrison (football player), currently a linebacker for the Pittsburgh Steelers.