Isoxazole is an azole with an oxygen atom next to the nitrogen.

Isoxazoles are found in some natural products, such as ibotenic acid. Isoxazoles also form the basis for a number of drugs, including the COX-2 inhibitor valdecoxib (Bextra). Furoxan is a nitric oxide donor.

See also

• Oxazole, an analog with the nitrogen atom in position 3.
• Pyrrole, an analog without the oxygen atom.
• Furan, an analog without the nitrogen atom.
• Simple aromatic rings

External links

• Synthesis of isoxazoles (overview of recent methods)

Nitrogen heterocycles | Oxygen heterocycles | Simple_aromatic_rings